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Promiscuous refers to an individual characterized by their transient sexual relationships. Typically, the term is used to refer to females. Many people consider it to be a derogatory term.
A promiscuous individual takes an undiscriminating or unselective approach to sexual relationships. One who has multiple casual relationships might be referred to as being promiscuous. Promiscuous individuals might also be referred to as sluts, whores, or harlots.