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Lube the tube refers to applying one's lubricant choice. The tube can be any orifice of one's liking, be it a vagina, anus, sex doll, or sex toy. The idea behind lubing the tube is to enhance the sexual experience and make it more pleasurable for both parties.
There are several choices when one wants to lube the tube. The two main options are water-based and silicone-based lubricants. Silicone-based lubricants last longer. Just a little drop can go a long way. However, these may compromise the materials used in condoms and many sex toys. Water-based lubricants are generally safer to use with condoms and toys. One just needs to lube the tube repeatedly to retain lubrication.